Hosting PacBio User Group Meeting June 27/28: Win Sequencing on our Sequel System

For the 5th year in a row, we’re proud to be hosting the annual PacBio East Coast User Group Meeting (UGM) & Workshops on June 27 & June 28 at the School of Pharmacy.  The UGM is a great opportunity to hear how scientists are using SMRT Sequencing to advance their research, a chance to learn best practices, and an opportunity to hear about application success stories. The agenda features speakers from Johns Hopkins University, The Jackson Laboratory, New England Biolabs, Massachusetts General Hospital and Harvard Medical School, University of Massachusetts Medical School, North Carolina State University, University of Florida & more. In addition, PacBio staff will be on-hand to answer questions, share insights, and talk about the technology road map.


Two SMRT Sequencing interactive workshops take place on campus on June 27th:

  • From 9am – 1pm, the Bioinformatics Workshop will highlight new tools available within SMRT Analysis 4.x. The PacBio Bioinformatics team will share analysis guidance for ensuring genomes are publication ready, as well as discuss various multiplexed analyses available through SMRT Link and enabled by the latest protocols for the Sequel System.
  • From 2pm – 6pm, the Sample Prep Workshop will cover product updates, application updates, and sample preparation recommendations to achieve the longest reads possible. Interactive group breakout sessions will facilitate discussions about specific applications of SMRT Sequencing.

Register online to attend these events.


New to PacBio sequencing?  We’re offering a chance to win sequencing and analysis on our new Sequel System.  The Microbial SMRT Grant program is open until June 30 and entering is simple: just submit a brief application describing how you’d use the long reads, high accuracy, single-molecule resolution, and uniform coverage of SMRT Sequencing to fully characterize viruses, microbes, and/or their communities.


One winner will be chosen by a panel of scientists. Submit your entry today!

GRC Launches NanoString nCounter services – Win free reagents!

We are pleased to announce the launch of our new NanoString services. The nCounter Analysis System has the ability to digitally quantify changes in up to 800 DNA, RNA, and protein targets using a single detector from samples of limited volume and concentration without the need for amplification or library preparation. With a technology that expands our capabilities and complements our high-throughput sequencing platforms, we are excited to have the NanoString nCounter join our growing family of services.

Please join us for a lunch seminar on Wednesday to learn more about the technology and our services:

Introduction to NanoString Technologies: Digital counting of proteins, mRNA, and DNA at 800-Plex from a single sample

RSVP here

Speaker: Kelly Miller, Ph.D. NanoString Field Applications Scientist
Wednesday, March 22nd, 2017
Seminar:  12:00pm – 1:00pm
Office Hours available: 1:30pm – 5:00pm

University of Maryland Life Sciences Conference Center
801 West Baltimore St.
Invent and Advance Rooms

Apply for our NanoString Technologies Grant Contest and win $5000 in NanoString reagents! Submit a brief (500 word max) proposal by April 21, 2017 via email. The winner will be announced on May 5, 2017. Click here for more information.

If you can’t make the seminar but would like more information about the nCounter platform or our services, please contact us.

ASM SMRT Grant Winner: Squirrel Microbiome!

We’re pleased to announce the winner of this year’s SMRT Grant, which launched during the American Society for Microbiology annual meeting this summer. The grant program, co-sponsored by PacBio and the Institute for Genome Sciences (IGS), was very competitive, with over 100 submitted proposals. From this broad range of entries, our judges faced quite a task choosing just one recipient for the grant.

Congratulations to Jessica Sieber from the University of Minnesota Duluth, who impressed reviewers with her proposal, “Metagenomic analysis of the gut microbiota of the 13-lined ground squirrel, a model fat storing hibernator.”

Ground squirrels have been models for human health conditions from diabetes and obesity to longevity and hypothermia. These particular squirrels are scientifically interesting because they almost triple their weight before going into a six-month hibernation, during which they consume nothing. Sieber notes that the hibernation process involves reducing the squirrel’s body temperature to 4 degrees Celsius. While that should be a challenging environment for the animal’s gut microbes, in fact they appear to thrive and may be responsible for folate production to protect the squirrel’s brain during hibernation. A deeper understanding of the role these microbiota play in this process may have downstream implications for human health.

Sieber’s project involves using SMRT Sequencing to produce a high-resolution picture of these gut microbial communities, including how they withstand the cold hibernation temperature. We look forward to learning about the new insights she discovers as a result of this grant!

In addition to the grant winner, the submitters of the top 10 proposals will have the opportunity to conduct their projects through IGS with a 20% discount on SMRT sequencing. Thank you to all of the submitters who participated in the grant competition. We look forward to a number of exciting new projects in the coming months!

Do you have a project that could benefit from SMRT sequencing or any of our other sequencing and analysis services? If so, please contact us for a free project consultation.

Do you have this year’s SMRTest Microbe? Apply Now!

As announced at ASM Microbe last month, the GRC and PacBio are once again co-sponsoring the “SMRTest Microbe” Grant Program. We are accepting research proposals for one more week!

Submit a short application (<250 words) describing your microbe or microbial community and how it would benefit from the long reads, high accuracy and direct detection of epigenetic modifications generated by SMRT Sequencing. One winner will be selected by a panel of scientists and will receive up to four library preparations and a sequencing run using up to eight SMRT Cells. Sequencing and bioinformatics analysis will be performed by the GRC, a PacBio Certified Service Provider.

Are you interested in microbial genomes, complex populations, or methylomes? If so, submit your proposals by July 15, 2016.

Other restrictions apply. See official rules.