Analysis - Analysis Engine

Recently, sequencing costs have dropped sharply due to increased throughput, simplification, and affordability of second (or even third and fourth) generation sequencing technologies, leading to an explosion of smaller sequencing facilities. However, despite the increased rate of sequence generation, there has not been a commensurate increase in access to computational resources to support high-quality sequence processing and analysis. To meet this need, we have developed the Analysis Engine which provides multiple analysis services including genome annotation, comparative genomics, and transcriptome analysis. We are also happy to talk to you about any custom analysis needs that you have. All analysis is available on a fee-for-service basis. Please contact us to tell us about your needs.

Prokaryotic Analysis Engine Services

Comparative genomics:
Automated whole genome comparisons that provide ortholog groups, syntenic regions and visualization of results using Sybil. Read more.

Transcriptome analysis:
Mapping of RNA-Seq reads to a reference genome and differential expression analysis. Read more.

Assembly of genomes with CloVR:
Prepacked assembly pipelines are available as virtual machines with CloVR.

Custom Analysis:
If you have analysis needs beyond what is outlined above, please contact us to discuss the needs of your project. We can provide custom analyses (for both prokaryotes and eukaryotes) on a fee-for-service basis.

Training workshops are available on many aspects of these analyses, please click here for more information

How to reference use of the IGS Analysis Engine in your publication
We ask that anyone using the IGS Analysis Engine for their work include that information in the Materials and Methods section and to acknowledge us in the Acknowledgements section. Thank You.

We gratefully acknowledge the National Institute of General Medical Sciences for funding earlier versions of this service.