SPARC (Search Procedures for Analysis of Residue Constraints)

SPARC computes DCA scores based on a typically large multiple sequence alignment and ranks each protein of known structure using STARC S-scores as a measure of  biological relevance. It can also identify transient interactions  between residue sidechains or backbones or between residues and ligands occurring during a MD simulation.  This facilitates interpretation of  sequence determinants of functional specificity identified by the DARC or BPPS programs. 

SPARC executable (beta release)