Genomics Resource Center

The Genomics Resource Center (GRC) is a high-throughput laboratory and data analysis group supporting the scientific programs of IGS and its collaborators, both across the University of Maryland Baltimore campus and across the globe. The GRC team has been an early-adopter and pioneer in genomic technology development for the past 25 years. Genomic technologies and applications now permeate both basic and clinical research. Using multiple sequencing and analysis platforms, the GRC generates high-quality genomic data in a cost-effective manner.

Personalized medicine is driven by genomic data. However, transforming this genomic data into scientific and medical knowledge is the primary challenge facing researchers today. With our long history and deep expertise in genomics, the GRC team is uniquely positioned to assist researchers facing this challenge.

Integrated, interdisciplinary approach
The GRC team includes scientists, bioinformaticians, project managers, and research specialists with extensive experience in planning and managing both small and large-scale projects. The GRC also works with world-renowned researchers in infectious disease, virology, microbial genomics and other areas, if you need additional resources.

Projects and processes
The GRC consults with each prospective researcher to develop a project plan that utilizes the most efficient and effective combination of available platforms and analysis pipelines to accomplish the goals of the project. This customized project plan serves to ensure the services provided by the GRC address the underlying scientific question(s) driving the project. The GRC strives to bring the increasing power and decreasing cost of genomic analysis to a continually expanding research community.

For more information or to discuss your research needs, please request more information or contact the GRC.

Pac Bio certified service provider


  • PacBio RS II
  • PacBio Sequel System
  • PacBio Sequel II System
  • Illumina NovaSeq 6000
  • Illumina HiSeq 4000 & HiSeq 2500
  • Illumina MiSeq
  • 10x Genomics Chromium
  • NanoString nCounter
  • Oxford Nanopore MinION

Sequencing Applications

  • DNA/RNA Extraction
  • Library Preparation
  • Genomes/Metagenomes
  • Exomes and Custom Capture
  • Transcriptomes/Metatranscriptomes
  • Epigenomes
  • Microbiome Amplicons (16S, 18S, ITS, etc.)
  • Single Cell Sequencing
  • Custom Amplicons
  • Digital Molecular Profiling
  • Customized Applications

Analysis Services

Provided in conjunction with the IGS Informatics Resource Center.

  • Assembly & Annotation
  • Comparative Genomics
  • Variant Analysis
  • Transcriptome Analysis
  • Epigenome Analysis
  • Microbiome Profiling
  • Pathway & Network Analysis
  • Microarray Analysis
  • Cloud Based Pipelines
  • Customized Analysis